Bully to your genetic monstrosity, Snafflehound! Bigger, better, more horrifying predators are the answer! Not sure about the question, but wow, the mythical Alaskan fur-bearing squid could finally become a reality!
As a lay person, I'm not fit to make any conclusive comment about areas where I've done little personal research, but the Arctic Ocean is the deepest body of water generally speaking (not counting fissures, trenches like the Challenger Deep, etc.) at about 12-15,000 feet deep. Post Cold War it's been revealed that one of the ways the Soviet Navy used to get rid of their old nuclear reactors was to dump them to the bottom, so I'm not sure how healthy an environment that might be for very sensitive creatures. Unless all those old Toho monster movies turn out to be correct, which I'm sad to say I doubt.